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Internationally Classified Substance Grouping

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Certain internationally classified substances are among those identified as priorities for action for the second phase of the Chemicals Management Plan (CMP). The selection of these internationally classified substances for action is based on the categorization process completed in 2006, and new information received as part of the first phase of the CMP.

Applying Significant New Activity Provisions

View the Comprehensive Listing of Substances that are subject to the Significant New Activity Provisions.

One substance, AEEA, may be addressed through the application of Significant New Activity (SNAc) provisions. One Notice of intent has been published. For additional guidance on submitting information required as part of SNAc notifications, please see the Guidelines for the Notification and Testing of New Substances: Chemicals and Polymers.

Summary of Publications

Internationally Classified Substances
CAS RN Chemical Substances Public Comments on the Draft Screening Assessment and Risk Management Scope Final Screening Assessment Proposed Risk Management Approach SNAc Application
95-48-7 o-cresol None HTML None  
106-44-5 p-cresol
108-39-4 m-cresol
1319-77-3 Mixed cresols
111-41-1 AEEA HTML HTML HTML
51-79-6 Carbamic acid, ethyl ester
(Ethyl carbamate)
None HTML HTML  
Timelines
Date Activity
If needed, information gathering tools could be used to inform potential risk management actions.
June 25, 2016Publication in Canada Gazette of Notice of intent to amend Domestic Substances List to apply the Significant New Activity provisions of the Canadian Environmental Protection Act, 1999 (CEPA 1999) to AEEA, and start of 60-day public comment period.
May 28, 2016 Publication in Canada Gazette of final assessment decisions under subsection 77(6) or section 68 of CEPA 1999, release of Government's proposed risk management approach document for ethyl carbamate, and start of 60-day public comment period on the proposed risk management approach document.
September 17, 2014 Deadline for submission of public comments on the draft screening assessments and the proposed risk management scope document on ethyl carbamate.
July 19, 2014 Publication in Canada Gazette and start of 60-day public comment period on (a) the draft screening assessments and (b) the risk management scope document on ethyl carbamate.
December 17, 2012 Deadline for submission of any voluntary information by interested stakeholders.
October 16, 2012 Deadline for submission of information for the section 71 Notice (without an extension).
June 16, 2012 Release of the section 71 Notice with respect to certain methylenediphenyl diisocyanate and diamine, and phenol, methyl- substances and the accompanying technical documents.

Final Screening Assessments and Proposed Risk Management Approach

In May 2016, three final screening assessments which collectively assess six substances were released and the related Notices were published in the Canada Gazette, Part I: Vol. 150, No. 22 – May 28, 2016 (PDF Version – 2,436 K).

The final screening assessments of AEEA and four cresols concluded that these five substances are not harmful to the environment or to human health and do not meet any of the criteria set out in section 64 of CEPA 1999. Therefore the Minister of the Environment and Climate Change and the Minister of Health proposed to take no further action on these substances at this time under the Act. No proposed risk management approach documents were prepared for these substances.

The final screening assessment of AEEA concluded that a risk to human health has not been identified for the general population of Canada at current levels of exposure. However, AEEA is recognized to have effects of concern based on its potential developmental and reproductive toxicity. There may be a concern for human health if exposures to the general population of Canada to AEEA were to increase, for example, through an increased presence in products available to consumers. Options for monitoring changes in uses of AEEA have been considered and application of the Significant New Activity (SNAc) provisions under subsection 81(3) of CEPA 1999 will be proposed. Stakeholders will have the opportunity to provide feedback on the Notice of Intent to apply the SNAc provisions to AEEA.

The final screening assessment of ethyl carbamate concluded that this substance is harmful to human health and meets the criteria set out under paragraph 64(c) of CEPA 1999. Risks to human health will be managed under the Food and Drugs Act, therefore, no further action under CEPA 1999 is proposed. A proposed risk management approach document for ethyl carbamate was also released on this date for a 60-day public comment period.

Draft Screening Assessments and Risk Management Scope

In July 2014, three draft screening assessments, which collectively assess six substances, were released and the related Notices were published in the Canada Gazette, Part I: Vol. 148, No. 24 - July 19, 2014 (PDF Version - 1,090 K). A risk management scope document for ethyl carbamate was also released in conjunction with these publications. There was a 60-day public comment period associated with each of these publications.

Submissions Received

Information on mixed creosols (CAS RN 1319-77-3; phenol, methyl-) was gathered from industry and interested stakeholders through a mandatory survey Notice issued under section 71 of CEPA 1999. Stakeholders were also invited to complete a voluntary questionnaire to inform the final assessment.

Submissions Received for the Internationally Classified Substance Grouping
Type of Response Number of Submissions
Mandatory section 71 Notice 8
Declaration of Stakeholder Interest 18
Voluntary Data Submissions (for example, studies, additional information) 24

Background

Section 71 Notice (Mandatory Survey)

In June 2012, a Notice was issued in the Canada Gazette, Part I: Vol.146, No.24 - June 16, 2012 ( PDF Version - 3,671 K) under section 71 of CEPA 1999. This Notice applied to 8 substances; specifically, 7 substances which are part of the Methylenediphenyl Diisocyanate and Diamine (MDI/MDA) Substance Grouping, and one substance (phenol, methyl-) which is part of the Internationally Classified Substance Grouping. Given similar data needs among the two substance groupings, the data requests were combined in this Notice. Every person to whom this Notice applied was required to comply with the Notice no later than 5 p.m. EDT, October 16, 2012.

If you have questions or comments, please Contact us. Indicate on the envelope or subject line "CMP Internationally Classified Substance Grouping".